Malgorzata Wygrecka Selected Research

Biglycan

1/2021	The Role of Decorin and Biglycan Signaling in Tumorigenesis.
1/2021	Biglycan: A regulator of hepatorenal inflammation and autophagy.
12/2020	Communications via the Small Leucine-rich Proteoglycans: Molecular Specificity in Inflammation and Autoimmune Diseases.
1/2020	Danger matrix molecules orchestrate CD14/CD44 signaling in cancer development.
1/2019	Breaking down chronic inflammatory diseases: the role of biglycan in promoting a switch between inflammation and autophagy.
1/2019	Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury.
1/2019	Biglycan is a new high-affinity ligand for CD14 in macrophages.
1/2018	Biglycan, a novel trigger of Th1 and Th17 cell recruitment into the kidney.
1/2018	Small Leucine-Rich Proteoglycans in Renal Inflammation: Two Sides of the Coin.
10/2017	Signaling at the Crossroads: Matrix-Derived Proteoglycan and Reactive Oxygen Species Signaling.

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Malgorzata Wygrecka Research Topics

Disease

21	Inflammation (Inflammations) 10/2022 - 10/2007
18	Idiopathic Pulmonary Fibrosis 01/2022 - 09/2008
15	Fibrosis (Cirrhosis) 10/2022 - 12/2008
11	Neoplasms (Cancer) 01/2021 - 03/2010
10	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2022 - 09/2012
8	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2022 - 07/2007
8	Pulmonary Hypertension 03/2020 - 09/2008
6	Lung Injury 08/2021 - 03/2008
6	Familial Primary Pulmonary Hypertension 01/2019 - 09/2008
5	Interstitial Lung Diseases (Interstitial Lung Disease) 10/2022 - 03/2008
5	Hypoxia (Hypoxemia) 01/2019 - 09/2008
4	Infections 10/2021 - 08/2008
4	Acute Lung Injury 01/2019 - 07/2007
3	Pneumonia (Pneumonitis) 10/2022 - 07/2007
3	Glioma (Gliomas) 11/2018 - 01/2017
3	Lung Diseases (Lung Disease) 03/2014 - 09/2004
2	Systemic Scleroderma (Systemic Sclerosis) 10/2022 - 01/2021
2	Carcinogenesis 01/2021 - 03/2010
2	Extrinsic Allergic Alveolitis (Hypersensitivity Pneumonitis) 01/2021 - 02/2009
2	Sarcoidosis (Schaumann Disease) 01/2021 - 02/2009
2	Kidney Diseases (Kidney Disease) 01/2021 - 01/2019
2	Reperfusion Injury 01/2019 - 01/2019
2	Chronic Obstructive Pulmonary Disease (COPD) 03/2014 - 09/2012
2	Vascular Remodeling 03/2014 - 04/2012
2	Lung Neoplasms (Lung Cancer) 09/2012 - 03/2010
1	COVID-19 01/2022
1	Human Influenza (Influenza) 01/2022
1	Critical Illness (Critically Ill) 01/2022
1	Septic Shock (Toxic Shock Syndrome) 11/2021
1	Liver Diseases (Liver Disease) 01/2021
1	Autoimmune Diseases (Autoimmune Disease) 12/2020
1	Pulmonary Arterial Hypertension 01/2019

Drug/Important Bio-Agent (IBA)

10	Bleomycin (Blenoxane)FDA LinkGeneric 10/2022 - 02/2009
10	BiglycanIBA 01/2021 - 10/2017
9	Proteins (Proteins, Gene)FDA Link 10/2021 - 10/2007
6	Peptide Hydrolases (Proteases)FDA Link 08/2013 - 06/2007
5	pirfenidoneIBA 10/2022 - 01/2017
5	FibrinIBA 01/2022 - 09/2004
5	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2020 - 01/2018
4	Small Leucine-Rich ProteoglycansIBA 01/2021 - 01/2018
4	Factor VII (Proconvertin)IBA 03/2008 - 06/2007
3	CollagenIBA 10/2022 - 11/2018
3	Factor XII (Hageman Factor)IBA 01/2022 - 04/2010
3	DecorinIBA 01/2021 - 01/2018
3	Proteoglycans (Proteoglycan)IBA 01/2021 - 01/2019
3	Cell Surface ReceptorsIBA 01/2021 - 11/2012
3	indium-bleomycinIBA 07/2020 - 09/2008
3	MonocrotalineIBA 01/2019 - 09/2008
3	Histones (Histone)IBA 01/2019 - 09/2012
3	RNA (Ribonucleic Acid)IBA 11/2016 - 07/2007
2	Plasminogen Activators (Plasminogen Activator)IBA 01/2022 - 07/2007
2	LigandsIBA 01/2022 - 12/2012
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2018
2	Hyaluronic Acid (Hyaluronan)IBA 01/2020 - 10/2017
2	Plasminogen Activator Inhibitor 1IBA 01/2020 - 07/2007
2	Protein-Arginine N-Methyltransferases (Methyltransferase, Protein Arginine)IBA 05/2018 - 12/2015
2	Transcription Factors (Transcription Factor)IBA 04/2018 - 09/2008
2	Pharmaceutical PreparationsIBA 01/2018 - 01/2017
2	InflammasomesIBA 01/2018 - 01/2018
2	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2017 - 02/2007
2	Matrix Metalloproteinases (MMPs)IBA 01/2017 - 08/2011
2	Fibrinolysin FDA Link 05/2015 - 11/2014
2	Chymases (Chymase)IBA 03/2014 - 01/2013
2	Proteinase-Activated ReceptorsIBA 08/2013 - 06/2011
2	Oxygen (Dioxygen)IBA 01/2013 - 02/2007
2	Thromboplastin (Tissue Factor)IBA 11/2012 - 06/2011
2	Becaplermin (PDGF-BB)FDA Link 04/2012 - 06/2007
2	Factor VIIa (Activated Factor VII)IBA 06/2011 - 03/2008
2	Heparin (Liquaemin)FDA LinkGeneric 06/2010 - 03/2008
2	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 03/2010 - 12/2008
2	Surface-Active Agents (Surfactants)IBA 12/2008 - 07/2007
2	Pulmonary Surfactants (Pulmonary Surfactant)IBA 07/2007 - 07/2007
1	Fibrinogen (Factor I)FDA Link 01/2022
1	Insulin-Like PeptidesIBA 01/2022
1	ErbB Receptors (EGF Receptor)IBA 01/2022
1	KaolinIBA 01/2022
1	Carboxypeptidase B2 (Thrombin Activatable Fibrinolysis Inhibitor)IBA 01/2022
1	Insulin-Like Growth Factor Binding ProteinsIBA 01/2022
1	Tissue Plasminogen Activator (Alteplase)FDA Link 01/2022
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 11/2021
1	Peroxidase (Myeloperoxidase)IBA 08/2021
1	nintedanibIBA 01/2021
1	FibromodulinIBA 12/2020
1	Biological ProductsIBA 12/2020
1	AlarminsIBA 12/2020
1	LumicanIBA 12/2020
1	palbociclibIBA 07/2020
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 07/2020
1	Vasodilator Agents (Vasodilators)IBA 03/2020
1	Synthetic DrugsIBA 01/2020
1	Versicans (Versican)IBA 01/2020
1	Lipoprotein Receptors (Lipoprotein Receptor)IBA 01/2019
1	AnionsIBA 01/2019
1	BenzbromaroneIBA 01/2019
1	EnzymesIBA 01/2019
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2019
1	LipidsIBA 01/2019
1	LipopolysaccharidesIBA 01/2019

Therapy/Procedure

6	Therapeutics 01/2021 - 02/2007
1	Plasma Exchange 11/2021